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Vtrace valve1/7/2023 ![]() An infection of the lining of the heart can damage the tricuspid valve. Infection of the lining of the heart (infective endocarditis).This complication of untreated strep throat can damage the tricuspid valve and other heart valves, causing valve regurgitation later in life. ![]() Marfan syndrome is a connective tissue disorder occasionally associated with tricuspid valve regurgitation. In this condition, the tricuspid valve is malformed and sits lower than usual in the right ventricle. Tricuspid valve regurgitation in children is usually caused by a rare congenital heart defect called Ebstein anomaly. Some congenital heart defects can affect the shape and function of the tricuspid valve. Heart defects present at birth (congenital heart defects).Tricuspid valve regurgitation can be caused by: As a result, blood leaks backward into the right atrium. In tricuspid valve regurgitation, the tricuspid valve doesn't close tightly. The valve flaps then close tightly to prevent the blood from moving backward. These valve flaps open to let blood flow from the upper right chamber (right atrium) to the lower right chamber (right ventricle). The tricuspid valve consists of three thin flaps of tissue (called cusps, or leaflets). The tricuspid valve sits between the heart's two right chambers. About half the people with Ebstein anomaly have an atrial septal defect. Atrial septal defect is a hole between the two upper chambers of the heart. Ebstein anomaly is a rare congenital heart defect in which the tricuspid valve is incorrectly formed and positioned lower than usual in the heart.
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